A Randomized Trial of Ready-to-Use Supplementary Food Versus Corn-Soy Blend Plus as Food Rations for HIV-Infected Adults on Antiretroviral Therapy in Rural Haiti

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A randomized trial of ready-to-use supplementary food versus corn-soy blend plus as food rations for HIV-infected adults on antiretroviral therapy in rural Haiti.

BACKGROUND The epidemics of food insecurity, malnutrition, and human immunodeficiency virus (HIV) frequently overlap. HIV treatment programs increasingly provide nutrient-dense ready-to-use supplementary foods (RUSFs) to patients living with HIV and food insecurity, but in the absence of wasting, it is not known if RUSF confers benefit above less costly food commodities. METHODS We performed ...

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Acceptability and use of ready-to-use supplementary food compared to corn–soy blend as a targeted ration in an HIV program in rural Haiti: a qualitative study

BACKGROUND Ready-to-use supplementary food (RUSF) is increasingly used as a component of food rations for adults with HIV. METHODS We undertook a qualitative study to evaluate the acceptability and use of peanut-based RUSF compared to corn-soy blend (CSB) among adults living with HIV in rural Haiti who had been enrolled in a prospective, randomized trial comparing the impact of those rations....

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Supplementary feeding with either ready-to-use fortified spread or corn-soy blend in wasted adults starting antiretroviral therapy in Malawi: randomised, investigator blinded, controlled trial

OBJECTIVE To investigate the effect of two different food supplements on body mass index (BMI) in wasted Malawian adults with HIV who were starting antiretroviral therapy. DESIGN Randomised, investigator blinded, controlled trial. SETTING Large, public clinic associated with a referral hospital in Blantyre, Malawi. PARTICIPANTS 491 adults with BMI <18.5. INTERVENTIONS Ready-to-use forti...

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Early versus standard antiretroviral therapy for HIV-infected adults in Haiti.

BACKGROUND For adults with human immunodeficiency virus (HIV) infection who have CD4+ T-cell counts that are greater than 200 and less than 350 per cubic millimeter and who live in areas with limited resources, the optimal time to initiate antiretroviral therapy remains uncertain. METHODS We conducted a randomized, open-label trial of early initiation of antiretroviral therapy, as compared wi...

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Cost-Effectiveness of Early Versus Standard Antiretroviral Therapy in HIV-Infected Adults in Haiti

BACKGROUND In a randomized clinical trial of early versus standard antiretroviral therapy (ART) in HIV-infected adults with a CD4 cell count between 200 and 350 cells/mm³ in Haiti, early ART decreased mortality by 75%. We assessed the cost-effectiveness of early versus standard ART in this trial. METHODS AND FINDINGS Trial data included use of ART and other medications, laboratory tests, outp...

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ژورنال

عنوان ژورنال: Clinical Infectious Diseases

سال: 2014

ISSN: 1537-6591,1058-4838

DOI: 10.1093/cid/ciu028